The 2022 Mercedes-Benz E-Class is a midsize luxury sedan with a reputation for power, elegance, safety, comfort, and versatility. For the 2022 model year, Mercedes’ long-running nameplate remains relatively unchanged following last year’s refresh to the cabin, exterior, and infotainment system.
Automatic high-beam headlights are now standard on all E-Class sedans, and one new color (Nautical Blue Metallic) is available.
While the sedan is the most well-known variant, the E-Class is offered as a coupe, convertible, and station wagon, too. This gives luxury-car shoppers a choice between a dash more style, open-air thrills, or a roomier cargo area for hauling lots of stuff.
For simplicity, we’ll focus on the primary trims and powertrains offered in the 4-door version of this German luxury car. For reference, rivals to the 2022 E-Class include the Audi A6, BMW 5 Series, Lexus ES, Acura TLX, and Cadillac CT5.
Keep reading to discover all there is to know about standard and optional features available on the 2022 E-Class sedan lineup.
2022 Mercedes-Benz E 350 ($54,950)
The 2022 Mercedes-Benz E 350 and E 350 4Matic are equipped with a 255-horsepower turbocharged 4-cylinder coupled to a 9-speed automatic transmission. The main mechanical change from one model to the other is the standard fitment of all-wheel drive (AWD) on the 4Matic – not to mention a price increase of $2,500.
At the time of writing, Mercedes-Benz had not formally announced pricing for its 2022 models. All prices mentioned here are estimated based on the previous year and applicable $1,050 destination fee.
Standard features are ample, and Mercedes gave tech touches a sizable upgrade for 2021. This includes a large and easy-to-used 12.3-inch infotainment screen, Apple CarPlay, Android Auto, navigation, HD radio, Bluetooth, and pair of front USB ports. The driver is also presented with a 12.3-inch digital gauge display positioned alongside the infotainment screen.
Comfort features include heated front seats, sunroof, dual-zone climate control, MB-Tex synthetic leather seating surfaces, hands-free trunk lid, and remote start, to name a few. When talk turns to safety, know that every 2022 E-Class sedan is equipped with automatic emergency braking, forward-collision warning, blind-spot monitors, rearview camera, and driver drowsiness monitor.
In addition to these, the E-Class features some unique touches like Pre-Safe Sound. This emits “pink noise” during an accident to protect the occupants’ ears from the noise caused during a serious collision.
There’s no shortage of cosmetic, luxury, and safety items that buyers can add when it comes to options. The AMG Line with Exterior Night Package costs roughly $1,150 and comes with upgraded brakes, gloss black exterior trim, and AMG 5-spoke alloy wheels.
More than a half-dozen wheels are offered, ranging from 18 to 19 inches in diameter. Also offered outside of a larger option package is a body-colored or black rear spoiler, panoramic roof, and LED logo projectors when the front doors are opened at night.
For a more controlled ride, the E 350 can be equipped with an air suspension for approximately $1,900.
Moving to the interior, cabin upgrades include Nappa leather seating surfaces, heated steering wheel, ventilated front seats, massaging front seats, power rear sunshade, wireless smartphone charging, two USB-C ports for the rear seat, combination wood-and-leather steering wheel, and about six choices of wood trim. Option groupings like the Warmth and Comfort Package include rapid-heating front seats, heated steering wheel, and heated front armrests.
The Premium Package is an interesting grouping that combines a Burmester audio system, rear cross-traffic alert, active parking assist, six months of satellite radio, and surround-view camera for around $2,300.
Buyers can have a safety-related suite of features via the Driver Assistance Package. At about $1,900 extra, it comes with 15 additional active safety items. These include evasive steering assist, adaptive cruise control, active blind spot assist, and active lane-keep assist, to name a few. Purchasers can also add a head-up display, gesture controls for the infotainment system, and augmented video for the navigation system.
Using our starting price of the 2022 E 350 sedan and a destination fee of $1,050, the E 350 has a price of $56,000. Financing that sum for 60 months at a 3% interest rate with zero money down at signing will cost $1,066 monthly. See 2022 Mercedes-Benz E 350 models for sale
2022 Mercedes-Benz E 350 includes:
- Punchy 4-cylinder – The 225-hp turbo 4-cylinder needs about 6.0 seconds to get the E-Class from zero to 60 mph.
- Safety – The E-Class comes with many safety features, including Pre-Safe Sound technology to protect occupants’ ears during a major accident.
- Room for five – With plenty of stretch-out space for adults in either the first or second row.
2022 Mercedes-Benz E 450 ($62,750)
The 2022 Mercedes-Benz E 450 comes standard with AWD and a more potent 369-horsepower turbocharged inline 6-cylinder engine. This powertrain comes with EQ Boost, a mild-hybrid system that helps improve fuel mileage while also giving a short jolt of added power and torque during hard acceleration.
According to its EPA-estimated mileage figures, the E 450 4Matic returns 23 mpg in city driving and 30 mpg on the highway. That’s almost identical to the MPG posted by the less-powerful E 350 in either RWD or AWD format.
The same standard and optional features found on the E 350 apply to the E 450. One minor difference is that heated rear seats are optional on the E 450 and not found on its less expensive sibling.
An E 450 buyer who finances $63,800 for 60 months at 3% interest and will pay $1,146 monthly with no money down. See 2022 Mercedes-Benz E 450 models for sale
2022 Mercedes-Benz E 450 includes:
- Standard AWD – The E 450 comes with Mercedes’ 4Matic AWD.
- Ride on air – Optional air suspension cushions the ride for long-distance comfort.
- Toasty rear seats – The E 450 has optional heated rear seats, a feature not offered on the E 350.
2022 Mercedes-AMG E 53 ($75,000)
The 2022 Mercedes-AMG E 53 comes with a retuned version of the turbocharged 6-cylinder engine found in the E 450. Good for a total of 429 horsepower, it’s also coupled to the EQ Boost mild-hybrid system and paired with a 9-speed automatic transmission. The first of two AMG variants also comes standard with AWD.
Considering its added performance, it’s no surprise the AMG E 53 gets larger brakes, firmer suspension, AMG exhaust, and 19-inch twin-5-spoke AMG wheels. Buyers can also choose alloy wheels up to 20 inches in diameter.
Further perks exclusive to the AMG E 53 include AMG crest logo projectors in the front doors, exterior badge deletion from the doors and rear decklid, flat-bottom steering wheel, Burmester 3D audio system, red seatbelts, soft-close doors, and cabin air purifier and scent diffuser.
An E-Class buyer looking to finance $76,050 for 60 months at a 3% interest rate with nothing down at signing can expect to pay $1,367 monthly. See 2022 Mercedes-AMG E 53 models for sale
2022 Mercedes-AMG E 53 includes:
- AMG hardware – AMG wheels, exhaust, and suspension settings are standard.
- Incognito – To travel quickly and under the radar for no extra money, exterior badge deletion is a $0 option.
- Interior – A flat-bottom AMG steering wheel and red seatbelts are available.
